Feedback regulation of mammalian ornithine decarboxylase. Studies using a transient expression system
نویسندگان
چکیده
منابع مشابه
Regulation of mammalian ornithine decarboxylase.
17 Melvin, M. A. L. and Keir, H. M. (1978) Expt. Cell Res. 111,231-236 18 Melvin, M. A. L. and Keir, H. M. (1979) Biochem. SOC. Trans. 7, 689-691 19 Wallace, H. M. and Keir, H. M. (1981) Biochim. Biophys. Acta 676,25-30 20 Melvin, M. A. L., Wallace, H. M. and Keir, H. M. (1980) Physiol. Chem. Phys. 12, 431-439 21 Coleman, C. S. and Wallace, H. M. (1990) 'Biochem. SOC. Trans. 18, 1228-1229 22 Wa...
متن کاملRegulation of Adrenal Ornithine Decarboxylase
were not secondary to stimulation of steroidogenesis, since hydrocortisone had no effect on adrenal ornithine decarboxylase although it did stimulate activity of the enzyme in the liver and kidney. ACTH, given subcutaneously to hypophysectomized rats, induced striking increases in adrenal cyclic AMP levels within 15-30 min with a fall towards the base line in 1 h. Increases in ornithine decarbo...
متن کاملRegulation of the expression of human ornithine decarboxylase gene and ornithine decarboxylase promoter-driven reporter gene in transgenic mice.
We have studied the regulation of the expression of ornithine decarboxylase with the aid of transgenic mice harbouring either functional human ornithine decarboxylase genes or the mouse ornithine decarboxylase promoter-driven chloramphenicol acetyltransferase fusion gene in their genome. We used three different stimuli which are well known to enhance ornithine decarboxylase activity in their ap...
متن کاملThe Functions and Regulation of Ornithine Decarboxylase
..............................................................................................................4 LIST OF ORIGINAL PUBLICATIONS...................................................................7 ABBREVIATIONS ...................................................................................................8 INTRODUCTION...............................................................
متن کاملScreening of microbial inhibitors of mammalian ornithine decarboxylase.
Sir: In the course of searching for inhibitors of mammalian ornithine decarboxylase (ODC), an active compound was isolated from the culture broth of an unidentified fungus and identified as citrinin, a known antibiotic1,2). Citrinin showed cytotoxicity in vitro to mouse leukemia cells. Structurally related compounds were examined for possible inhibition of ODC and cytotoxicity, and we found tha...
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ژورنال
عنوان ژورنال: European Journal of Biochemistry
سال: 1993
ISSN: 0014-2956,1432-1033
DOI: 10.1111/j.1432-1033.1993.tb18089.x